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#programmable

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J. Rosenbaum (they/them)<p>I had a blast at <a href="https://wandering.shop/tags/programmable" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>programmable</span></a> this week. I'm exhausted but really pleased with how my talk was received. It is a more challenging, darker talk than I usually do, but important because it is emblematic of what is happening right now. Here are some random pics of the week!</p>
lachlan slowly taming rust<p>Anybody attending <a href="https://mastodon.social/tags/Programmable" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Programmable</span></a> <a href="https://mastodon.social/tags/Melbourne" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Melbourne</span></a>?</p>
Su_G<p><span class="h-card" translate="no"><a href="https://mastodon.xyz/@401matthall" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>401matthall</span></a></span> <span class="h-card" translate="no"><a href="https://mstdn.social/@Remittancegirl" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>Remittancegirl</span></a></span> </p><p>That is a stunning piece of Census information, that 8 in 10 Americans live within 100 miles of where they grew up (6 in 10 within 10 miles)...</p><p>and then: "Most Americans don't know anything about the world around them from their own experience. It's all fed to us via a screen. We are eminently programmable." 😐 </p><p><a href="https://aus.social/tags/Consequences" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Consequences</span></a> <br><a href="https://aus.social/tags/USCensus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>USCensus</span></a><br><a href="https://aus.social/tags/programmable" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>programmable</span></a></p>
Jon Moller<p><span class="h-card"><a href="https://social.politicaconciencia.org/@Maya" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>Maya</span></a></span> <span class="h-card"><a href="https://bsd.network/@claudiom" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>claudiom</span></a></span> <span class="h-card"><a href="https://tilde.zone/@gemlog" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>gemlog</span></a></span> <span class="h-card"><a href="https://tilde.zone/@nytpu" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>nytpu</span></a></span> <span class="h-card"><a href="https://retro.social/@kelbot" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>kelbot</span></a></span> <span class="h-card"><a href="https://mastodon.sdf.org/@goosey" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>goosey</span></a></span> <span class="h-card"><a href="https://mastodon.sdf.org/@xmanmonk" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>xmanmonk</span></a></span> <span class="h-card"><a href="https://mastodon.sdf.org/@robert588" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>robert588</span></a></span> Some fun <a href="https://mastodon.sdf.org/tags/reviewing" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>reviewing</span></a> my <a href="https://mastodon.sdf.org/tags/texasinstruments" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>texasinstruments</span></a> <a href="https://mastodon.sdf.org/tags/ti66" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ti66</span></a> <a href="https://mastodon.sdf.org/tags/programmable" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>programmable</span></a> <a href="https://mastodon.sdf.org/tags/calculator" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>calculator</span></a> built by <a href="https://mastodon.sdf.org/tags/toshiba" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>toshiba</span></a>. Super slow but great battery life. A <a href="https://mastodon.sdf.org/tags/4bit" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>4bit</span></a> <a href="https://mastodon.sdf.org/tags/turingcomplete" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>turingcomplete</span></a> <a href="https://mastodon.sdf.org/tags/computer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>computer</span></a> in your pocket. <a href="https://youtu.be/BBPO8ZeGoE4" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="">youtu.be/BBPO8ZeGoE4</span><span class="invisible"></span></a></p>
Chuck Darwin<p>Researchers uncover a new CRISPR-like system in animals that can edit the human genome </p><p>A team of researchers led by Feng Zhang at the McGovern Institute for Brain Research at MIT and the Broad Institute of MIT and Harvard has uncovered the first <a href="https://c.im/tags/programmable" class="mention hashtag" rel="tag">#<span>programmable</span></a> <a href="https://c.im/tags/RNA" class="mention hashtag" rel="tag">#<span>RNA</span></a>-<a href="https://c.im/tags/guided" class="mention hashtag" rel="tag">#<span>guided</span></a> system in <a href="https://c.im/tags/eukaryotes" class="mention hashtag" rel="tag">#<span>eukaryotes</span></a> — organisms that include fungi, plants, and animals.</p><p>In a study published today in Nature, the team describes how the system is based on a protein called <a href="https://c.im/tags/Fanzor" class="mention hashtag" rel="tag">#<span>Fanzor</span></a>. They showed that Fanzor proteins use RNA as a guide to target DNA precisely, and that Fanzors can be reprogrammed to edit the genome of human cells. </p><p>The <a href="https://c.im/tags/compact" class="mention hashtag" rel="tag">#<span>compact</span></a> Fanzor systems have the potential to be more easily delivered to cells and tissues as therapeutics than <a href="https://c.im/tags/CRISPR" class="mention hashtag" rel="tag">#<span>CRISPR</span></a>-<a href="https://c.im/tags/Cas" class="mention hashtag" rel="tag">#<span>Cas</span></a> systems, and further refinements to improve their targeting efficiency could make them a valuable new technology for human <a href="https://c.im/tags/genome" class="mention hashtag" rel="tag">#<span>genome</span></a> <a href="https://c.im/tags/editing" class="mention hashtag" rel="tag">#<span>editing</span></a></p><p><a href="https://news.mit.edu/2023/fanzor-system-in-animals-can-edit-human-genome-0628" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">news.mit.edu/2023/fanzor-syste</span><span class="invisible">m-in-animals-can-edit-human-genome-0628</span></a></p>